本文从胰岛素的免疫化学效价变化、高分子化合物生成量和脱酰胺基等方面研究胰岛素的稳定性,测定胰岛素转变为高分子物和脱酰胺胰岛素的速度常数及活化能。实验用100mg 精制胰岛素密封在洁净的软玻璃小瓶内,分别在60、50、37、25、5°及-20°暗处贮藏,于第3、6和12个月后取样,分别以凝胶过滤层析法、聚丙烯 In this paper, we studied the stability of insulin from the change of immunochemical titer of insulin, the amount of polymer compound and deamidation, and determined the rate constants and activation energy of insulin to polymer and deamidated insulin. Experiments with 100mg refined insulin sealed in clean soft glass vials, respectively, at 60,50,37,25,5 ° and -20 ° dark storage at the 3rd, 6th and 12 months after sampling, respectively, the gel Filter chromatography, polypropylene