目的优化地榆总皂苷的酸水解工艺,提高水解产物地榆皂苷元的产量。方法采用正交试验设计,考察盐酸浓度、料液比、水解温度、水解时间对地榆总皂苷水解过程的影响。结果影响水解的主次因素依次是盐酸浓度>水解时间>料液比>水解温度,优选的最佳工艺为料液比1∶200,盐酸浓度为4 mol/L,水解时间0.5 h,水解温度92℃。结论采用优化后的水解条件能够得到产量较高的地榆皂苷元,适合工业化生产。 Objective To optimize the acid hydrolysis process of Ulmus pumila and to increase the production of saurin from hydrolysates. Methods Orthogonal design was used to study the effects of hydrochloric acid concentration, solid-liquid ratio, hydrolysis temperature and hydrolysis time on the total saponin hydrolysis process. Results The main factors affecting the hydrolysis followed by hydrochloric acid concentration> hydrolysis time> solid-liquid ratio> hydrolysis temperature. The optimum conditions were as follows: solid-liquid ratio 1: 200, hydrochloric acid concentration 4 mol / L, hydrolysis time 0.5 h, hydrolysis temperature 92 ° C. Conclusion Sapogenin with higher yield can be obtained by using optimized hydrolysis conditions, which is suitable for industrialized production.