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目的:观察帕宁方治疗帕金森病(PD)的临床疗效。方法:将81例患者随机分成治疗组和对照组,对照组给予美多巴治疗,治疗组加服帕宁方,每日一剂,水煎,分2次服,疗程均为12周。观察两组临床疗效及治疗前后的帕金森病改良的统一评分量表(UPDRS)评分、改良的Hoehn﹠Yahr(H-Y)分级情况、美多巴使用量及不良反应。结果:治疗组的UPDRS评分、临床疗效明显优于对照组(P<0.05),两组的H-Y分级和美多巴使用量无显著性差异(P>0.05),治疗组2例出现恶心、胃肠胀气,无其他不良反应。结论:联合帕宁方治疗可以明显改善PD患者症状,增强效疗,提高生活质量。
Objective: To observe the clinical effect of Panning Recipe in treating Parkinson’s disease (PD). Methods: Eighty-one patients were randomly divided into treatment group and control group. The control group was treated with methyclopaedine. The treatment group was treated with Parinib, once daily, and decocted for 2 weeks. The course of treatment was 12 weeks. The UPDRS score, modified Hoehn & Yahr (H-Y) classification, and the dose and side effects of metoprolol in the two groups were observed before and after treatment. Results: The UPDRS score of the treatment group was significantly better than that of the control group (P <0.05). There was no significant difference in HY classification between the two groups (P> 0.05). The treatment group had nausea and gastrointestinal Flatulence, no other adverse reactions. Conclusion: The combination of Panning Fang can significantly improve the symptoms of PD patients, enhance the efficacy and improve the quality of life.