目前研究用限制饮食蛋白作为鼠类肾次全切除肾衰模型和链脲霉素糖尿病模型的治疗方式。在两者中饮食蛋白限制使升高的肾小球毛细血管压和流量正常化,并且减少蛋白尿至正常水平和阻止形态学病变。在肾次全切除模型的长期研究中,确实显示了喂予低蛋白饮食的鼠类的肾衰发病率有明显的减少。 Current research uses dietary protein restriction as a model for the treatment of renal sub-total renal allograft rejection and streptozotocin in diabetic rats. Dietary protein restriction regulates elevated glomerular capillary pressure and flux in both, and decreases proteinuria to normal levels and prevents morphological lesions. In the long-term study of the subtotal nephrectomy model, there was indeed a clear reduction in the incidence of renal failure in mice given the low-protein diet.