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目的比较前列腺绿激光光汽化术与经尿道前列腺电切术治疗晚期前列腺癌伴膀胱出口梗阻的安全性及有效性。方法40例晚期前列腺癌伴有膀胱出口梗阻的患者随机分成激光组和电切组,分别采用绿激光光汽化术和电切术进行姑息性治疗,并同时联合药物去势加雄激素受体阻断的间歇性治疗方案,随访6～96个月。结果激光组术中术后出血、导尿管留置时间、住院天数、手术并发症均明显低于电切组(P<0.05);两组术后1个月国际前列腺症状评分(IPSS)、最大尿流率(Qmax)和残余尿量(PVR)与术前相比均有明显改善(P<0.01)。结论与电切术相比,绿激光光汽化术治疗晚期前列腺癌具有创伤小、出血少、恢复快,并能够有效减少手术并发症。
Objective To compare the safety and efficacy of laser photocoagulation with transurethral resection of prostate for the treatment of advanced prostate cancer with bladder outlet obstruction. Methods Forty patients with advanced prostate cancer accompanied with bladder outlet obstruction were randomly divided into laser group and transurethral resection group. The patients were treated with palliative treatment with green laser photocoagulation and electrotomy respectively. Combined with castration and androgen receptor blockade Broken intermittent treatment program, followed up for 6 to 96 months. Results The postoperative bleeding, catheter retention time, length of hospital stay, and surgical complications in the laser group were significantly lower than those in the resection group (P <0.05). The International Prostate Symptom Score (IPSS) Urinary flow rate (Qmax) and residual urine volume (PVR) were significantly improved compared with preoperative (P <0.01). Conclusion Compared with the resectoscope, green laser photocoagulation for the treatment of advanced prostate cancer with less trauma, less bleeding, rapid recovery, and can effectively reduce the surgical complications.