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目的:探讨长松联合马来酸曲美布汀治疗便秘型肠易激综合征(C-IBS)的疗效观察。方法:选择90例C-IBS进行随机对照试验。观察组30例,用马来酸曲美布汀200 mg,3次/d,长松1包,2次/d;对照A组30例,用长松1包,2次/d;对照B组30例,用马来酸曲美布汀200 mg,3次/d。疗程均为4周。对腹痛或腹部不适、排便频率和粪便性状改变等症状记分。结果:治疗前后比较,观察组的疗效明显优于对照A组或对照B组。3组总有效率比较有统计学差异(P<0.05)。结论:长松联合马来酸曲美布汀治疗C-IBS的一种较好选择。
Objective: To investigate the curative effect of long pine combined with trimebutine maleate in the treatment of constipation-induced irritable bowel syndrome (C-IBS). Methods: 90 cases of C-IBS were selected for randomized controlled trials. 30 patients in the observation group were treated with trimebutine maleate 200 mg three times a day for 2 times a day for 30 days. Group 30 cases, trimebutine maleate 200 mg, 3 times / d. The course of treatment is 4 weeks. On abdominal pain or abdominal discomfort, defecation frequency and changes in stool symptoms and other symptoms score. Results: Before and after treatment, the observation group was significantly better than the control group A or control group B. The total effective rate of 3 groups was statistically significant (P <0.05). Conclusion: Chang-song combined with trimebutine maleate C-IBS treatment of a better choice.