无创机械通气在重症肺炎合并急性呼吸衰竭中的疗效分析

来源 :中国实用医药 | 被引量 : 0次 | 上传用户:jsnjwh
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
目的研究无创机械通气(NPPV)治疗重症肺炎合并急性呼吸衰竭(SP-ARF)的临床疗效。方法 60例重症肺炎合并急性呼吸衰竭患者在征得患者家属同意的前提下随机分为两组,所有患者均在常规治疗的前提下,观察组应用NPPV治疗,对照组给予鼻导管吸氧,观察对比两组患者治疗前后血气分析和临床症状、体征等指标。结果两组患者治疗前血气分析指标pH、PaO2、PaCO2指标差异均无统计学意义(P>0.05);经过治疗之后,两组患者上述指标均显著下降,差异均有统计学意义(P<0.05);观察组治疗之后上述指标均显著低于对照组,差异有统计学意义(P<0.05)。观察组因病情恶化改有创机械通气3例(10.00%),对照组改有创机械通气14例(46.67%),两组差异有统计学意义(P<0.05);观察组平均住院时间(12.57±5.30)d,显著少于对照组(21.48±6.30)d,差异有统计学意义(P<0.05);因患者出现病情恶化改有创机械通气,观察组抢救无效死亡1例(3.33%),对照组3例(3.33%),两组差异无统计学意义(P>0.05)。结论 NPPV在临床应用效果满意,临床效果优于单纯应用鼻导管吸氧的方式,在有条件的医院应推广应用,但在应用过程中,在发现无创正压通气控制病情困难时,应尽早行有创正压机械通气(IPPV)治疗。 Objective To study the clinical efficacy of noninvasive mechanical ventilation (NPPV) in the treatment of severe pneumonia complicated with acute respiratory failure (SP-ARF). Methods Sixty patients with severe pneumonia complicated with acute respiratory failure were randomly divided into two groups with the consent of their families. All patients were treated with NPPV under the conventional treatment, while those in the control group were given nasal oxygenation and observation. Blood gas analysis and clinical symptoms, signs and other indicators before and after treatment were compared between two groups of patients. Results Before treatment, there was no significant difference of pH, PaO2 and PaCO2 between two groups (P> 0.05). After treatment, the above indexes of both groups were significantly decreased (P <0.05 ); The observation group after treatment the above indicators were significantly lower than the control group, the difference was statistically significant (P <0.05). In the observation group, invasive mechanical ventilation was changed in 3 cases (10.00%) due to the exacerbation of the disease and in 14 cases (46.67%) in the control group. The difference between the two groups was statistically significant (P <0.05) 12.57 ± 5.30) d, which was significantly lower than that of the control group (21.48 ± 6.30) d (P <0.05). One patient (3.33% ) And 3 cases (3.33%) in the control group. There was no significant difference between the two groups (P> 0.05). Conclusions NPPV is satisfactory in clinical application and its clinical effect is superior to that of simple nasal catheter oxygen inhalation. It should be popularized and applied in qualified hospitals. However, NPPV should be applied as soon as possible when it is found that noninvasive positive pressure ventilation is difficult to control Invasive positive pressure mechanical ventilation (IPPV) treatment.
其他文献
糖尿病患者的血压水平普遍高于普通人群,而血压的升高已被证实是糖尿病患者的一项危险因素。目前,降压治疗在糖尿病综合治疗中的应用尚存在争议,尤其是哪些患者应接受降压治疗以
“十月怀胎,一朝分娩”。对于每一位妇女来讲都是一段艰难的历程。孕妇始终承受着身体变化的负担及种种心理上的压力。而产痛的到来,会使孕妇焦虑、紧张及恐惧的心理达到高峰
目的 探讨老年肺结核患者应用抗肺结核药物过程中并发不良反应的护理措施.方法 选取我院收治的老年肺结核病患者86例,初次进行治疗的肺结核患者均给予一线抗结核治疗方案(3HR
内容简介:本书从动脉系统的解剖、生理及血流动力学三方面介绍了动脉系统的医学基础知识,从动脉硬化的病因、病理、症状、检查、诊断、常用治疗及预防保健等方面,详细介绍了冠状
期刊
目的:探讨彩色M型多普勒超声在评价高血压患者左心室舒张功能时是否受年龄影响及其价值。方法原发性高血压患者60例为观察组,并选取健康志愿者40例为对照组,选择心尖四心腔切面,
目的:探讨艾迪注射液对乳腺癌患者外周血淋巴细胞的影响。方法治疗组化疗后给予艾迪注射液治疗;对照组来给予特殊治疗。采用流式细胞仪等技术检测治疗组78例和对照组62例的外周
2015年执业药师考试落下帷幕已有2个月,考生试后表现出欢呼雀跃,高兴之情溢于言表,不知这是否与药店GSP大限来临,国家执业药师题目会偏易,放水的传言相吻合.如果是真的话,这
目的探讨雾化吸入沐舒坦(盐酸氨溴索注射液)联合酮替芬治疗小儿咳嗽变异性哮喘的临床治疗效果。方法 81例咳嗽变异性哮喘患儿,根据治疗方法随机分为治疗组47例和对照组34例,
目的:研究有氧运动对中老年大鼠主动脉晚期氧化蛋白产物(Aopps)含量及主动脉管壁结构的影响,探讨规律有氧运动对主动脉的保护机制.方法:健康雌性18月龄SD大鼠30只,随机分为中