Dacogen静脉滴注需持续3h以上,给药剂量为15mg/m2,每8h重复1次,共3天。Dacogen能导致中性粒细胞减少和血小板减少。每个疗程开始之前以及需要监测治疗反应和毒性时都要进行全血和血小板计数,如发生以下情况则要停止Dacogen治疗:血清肌酐≥2mg/dL;血清谷丙转氨酶(SGPT)、总胆红素≥正常值上限的2倍;有活动性或未控制的感染。对于接受Dacogen治疗的患者,临床医生应考虑给予生长因子和(或)抗生素治疗,以预防感染。 Dacogen intravenous infusion should be continued for more than 3h, the dose of 15mg / m2, repeated every 8h, a total of 3 days. Dacogen causes neutropenia and thrombocytopenia. Whole blood and platelet counts are taken before each course of treatment and when treatment response and toxicity need to be monitored. Dacogen treatment should be discontinued if: serum creatinine ≥ 2 mg / dL; serum alanine aminotransferase (SGPT), total bilirubin Prime ≥ 2 times the upper limit of normal; active or uncontrolled infection. For patients receiving Dacogen, clinicians should consider giving growth factors and / or antibiotics to prevent infection.