脉络膜黑色素瘤是成年人眼部最好发的恶性肿瘤,近年研究发现一些对脉络膜黑色素瘤发生起关键作用的异常的分子信号传导途径,如RTK(受体酪氨酸激酶)信号途径的过度激活,CDK(细胞周期素依赖性激酶)信号途径的失活等,及其相关基因的异常,导致肿瘤的生成和增殖。随着对脉络膜黑色素瘤发病的分子机制认识的深入,出现了一些新型的治疗方法。 Choroidal melanoma is one of the best malignant tumors in adult eyes. In recent years, some abnormal molecular signaling pathways that play a key role in choroidal melanoma have been found, such as overactivation of RTK (receptor tyrosine kinase) signaling pathway , Inactivation of CDK (cyclin-dependent kinase) signaling pathway and the like, as well as the abnormality of related genes, resulting in the generation and proliferation of tumors. With the deepening understanding of the molecular mechanism of the pathogenesis of choroidal melanoma, there are some new treatments.