We report the synthesis of Nd-filled and Fe substituted p-type NdxFe3.2Co0.8Sb12 (x=0.5, 0.6, 0.7, 0.8, and 0.9) skutterudites by the solid-state reaction method. The influences of Nd filler on the electrical and thermal transport prop-erties are investigated in a temperature range from room temperature to 850 K. A lowest lattice thermal conductivity of 0.88 W·m?1·K?1 is obtained in Nd0.8Fe3.2Co0.8Sb12 at 673 K, which results from the localized vibration modes of fillers and the increase of grains boundaries. Meanwhile, the maximum power factor is 2.77 mW·m?1·K?2 for the Nd0.9Fe3.2Co0.8Sb12 sample at 668 K. Overall, the highest dimensionless figure of merit zT =0.87 is achieved at 714 K for Nd0.9Fe3.2Co0.8Sb12.