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动脉粥样硬化是威胁人类健康的一类心血管疾病，如何抗动脉粥样硬化成为广大学者一直研究的重要课题之一。抗微生物肽LL-37及其形成的复合物在动脉粥样硬化斑块中的成功检测，为研究者在微生物领域研究动脉粥样硬化的发生、发展提供了理论支持，本文就抗微生物肽的一些作用特别是在动脉粥样硬化中的作用作一综述。“,”Atherosclerosis has become a class of cardiovascular diseases ,threatening to human health .How to resist the lesion has become an important issue in the majority of scholars .LL-37 and its complex detected successfully in the athero-sclerotic plaques provide a theoretical support for researchers in the development of atherosclerosis in microbial research .This review is aim to elucidate the effect of antimicrobial peptide LL-37 especially in the atherosclerosis .