论文部分内容阅读
目的:探讨注射用硫普罗宁与溶媒配伍后的输液滴速对肝功能异常疗效的影响。方法:采用单纯硫普罗宁治疗的肝功能异常患者74例随机分为观察组与对照组各37例,观察组硫普罗宁输液滴速为60~65滴/min,输液时间控制在1 h内;对照组输液滴速为30~35滴/min,输液时间控制在2 h内;疗程均为4周。比较两组患者临床疗效及肝功能改善情况。结果:观察组总有效率为83.78%,明显优于对照组的56.76%(P<0.05);两组的AST、ALT、TBIL均比治疗前明显下降(P<0.05),且观察组降低幅度明显优于对照组(P<0.05)。结论:注射用硫普罗宁在临床应用中,严格控制输液时间和输液滴速,能有效的提高其临床疗效。
Objective: To investigate the effects of intravenous drip infusion with sulfur and pramipexole on the efficacy of liver dysfunction. Methods: Thirty-seven patients with abnormal liver function treated with tiopronin were randomly divided into observation group (37 cases) and control group (37 cases). The infusion rate of tiopronin in the observation group was 60-65 drops / min and the infusion time was controlled within 1 h ; The infusion rate of the control group was 30-35 drops / min, the infusion time was controlled within 2 h; the courses of treatment were 4 weeks. The clinical efficacy and improvement of liver function were compared between the two groups. Results: The total effective rate in the observation group was 83.78%, which was significantly better than that in the control group (56.76%, P <0.05). The AST, ALT and TBIL in both groups were significantly lower than those before treatment (P <0.05) Obviously superior to the control group (P <0.05). Conclusion: In the clinical application of tiopronin for injection, strict control of infusion time and infusion drip rate can effectively improve its clinical efficacy.