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为了观察低氧暴露对急性常氧运动后机体自由基代谢的影响。对8名男性受试者以75%V·O2max强度蹬功率自行车1h后,分别在低氧(15.4%O2)和常氧环境中休息30min,测定运动前、运动后即刻和运动后30min红细胞和血清中超氧化物岐化酶(SOD)、丙二醛(MDA)和还原型谷光苷肽(GSH)的含量。结果显示:运动后即刻,红细胞MDA和血清GSH含量较运动前有显著升高,血清MDA、SOD和红细胞SOD无显著变化;运动后常氧恢复30min,红细胞MDA还处于高水平,但GSH恢复到运动前水平。运动后低氧30min恢复,红细胞MDA和血清GSH还是高于运动前水平,且血清GSH较运动后即刻还要高。结论:常氧运动后低氧暴露不利于体内自由基的恢复。
In order to observe the effects of hypoxic exposure on free radical metabolism in the body after acute normoxia. Eight male subjects were pedaled for 1 hour with 75% V · O2max power, and then were rested for 30 minutes in hypoxia (15.4% O2) and normoxia respectively. The levels of erythrocyte and Serum superoxide dismutase (SOD), malondialdehyde (MDA) and reducing glutathione peptide (GSH) content. The results showed that the content of MDA and serum GSH in erythrocytes and serum GSH were significantly higher than those before exercise, and there was no significant change in serum MDA, SOD and erythrocyte SOD. After exercise for 30 minutes, the MDA in erythrocytes was still high but the GSH was restored to Pre-exercise level. After 30min of hypoxia, red cell MDA and serum GSH were still higher than those before exercise, and serum GSH was higher immediately after exercise. Conclusion: Hypoxic exposure after normoxic exercise is not conducive to the recovery of free radicals.