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通过短期观察信号平均心电图（ＳＡ－ＥＣＧ）的重复性及比较心室晚电位（ＶＬＰ）阳性患者服药前后ＳＡ－ＥＣＧ指标变化，以了解长效二氢奎尼丁（ｓéｒéｃｏｒ）、普罗帕酮、美托洛尔对ＶＬＰ阳性患者ＳＡ－ＥＣＧ指标的影响，及是否具有逆转ＶＬＰ的作用，结果表明：（１）ＳＡ－ＥＣＧ各定量指标的重复性良好，ＶＬＰ阳性组自然转阴率仅为７．７％。（２）ｓｅｒｅｃｏｒ不能逆转ＶＬＰ，而具有选择性延长ＱＲＳ终末部４０μＶ的低振幅信号持续时间（ＬＡＳ）的作用。（３）普罗帕酮不能逆转ＶＬＰ，仅延长滤波后ＱＲＳ－时限（ＱＲＳ－Ｄ）。（４）美托洛尔显著逆转ＶＬＰ，使ＱＲＳ－Ｄ、ＬＡＳ缩短，综合导联滤波的ＱＲＳ终末４０ｍｓ处综合向量电压（ＲＭＳ_（４０））增加。讨论了三种抗心律失常药物对ＶＬＰ影响的不同效应。
By observing the repeatability of the signal-averaged electrocardiogram (SA-ECG) and comparing the change of SA-ECG before and after taking the drug in patients with positive ventricular late potentials (VLP) to find out the effect of sérécor, propafenone, The results showed that: (1) The reproducibility of each quantitative index of SA-ECG was good, and the natural conversion rate of VLP-positive group was only 7. 7%. (2) Serecor can not reverse VLP and has the effect of selectively prolonging the low amplitude signal duration (LAS) of 40 μV of the QRS terminal. (3) Propafenone did not reverse VLP and only prolonged QRS-time after filtering (QRS-D). (4) Metoprolol significantly reversed VLP and shortened QRS-D and LAS, and the integrated vector voltage (RMS_ (40)) increased at 40 ms after filtering with integrated lead filter. The different effects of three antiarrhythmic drugs on VLPs were discussed.