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尽管病毒性丙型肝炎(HCV)感染者血清中有多种抗HCV结构蛋白和非结构蛋白的抗体,但其体内仍有病毒血症的存在,同时动物实验亦表明已发生HCV感染的黑猩猩仍能被同种或异种的HCV株再次感染,这就提示感染者体内所产生的并非是特异性中和抗体,或抗体效价不能起到清除HCV感染的作用。
Although viral sera from patients with viral hepatitis C (HCV) have multiple antibodies against HCV structural and non-structural proteins, they still have viremia in their bodies, and animal experiments have also shown that HCV-infected chimps are still Can be re-infected with allogeneic or heterologous HCV strains, suggesting that the infected person is not producing specific neutralizing antibodies or that antibody titers do not clear HCV infection.