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目的探讨妊娠合并血小板减少的病因、结局及处理。方法回顾性分析123例妊娠合并血小板减少孕妇的病因,并分析其妊娠结局。结果主要病因为妊娠相关性血小板减少、特发性血小板减少性紫癜,妊娠高血压疾病及妊娠合并肝脏疾病;血小板计数<50×109/L者剖宫产率、输血率、新生儿窒息率明显高于(50～100)×109/L者(P<0.05);妊娠合并高血压、肝脏疾病引起的血小板减少患者早产、产后出血、新生儿窒息率明显高于其他病因者(P<0.05)。结论妊娠合并血小板减少患者剖宫产率及输血率与血小板减少程度有关,而产后出血、早产、新生儿窒息等与其病因密切相关。
Objective To investigate the etiology, outcome and treatment of pregnancy complicated thrombocytopenia. Methods Retrospective analysis of 123 cases of pregnant women with thrombocytopenia etiology, and analyze the pregnancy outcome. Results The main causes of pregnancy-related thrombocytopenia, idiopathic thrombocytopenic purpura, pregnancy-induced hypertension and pregnancy-associated liver disease; cesarean section with platelet count <50 × 109 / L, transfusion rate, neonatal asphyxia was significantly (50 ~ 100) × 109 / L (P <0.05). Premature labor and postpartum hemorrhage in neonates with thrombocytopenia caused by pregnancy complicated with hypertension and liver diseases were significantly higher than those with other causes (P0.05) . Conclusions Cesarean section rate and transfusion rate in patients with pregnancy complicated with thrombocytopenia are related to the degree of thrombocytopenia. Postpartum hemorrhage, premature delivery and neonatal asphyxia are closely related to etiology.