论文部分内容阅读
目的:探讨高脂血症对新疆哈萨克族正常血压组和高血压组左室重构及左心功能的影响。方法:选取新疆昌吉地区352例哈萨克族人群作为研究对象,其中正常血压组(NT)213例,高血压组(EH)139例,常规测量左心室舒张末朋内径(LVEDd)、左心室收缩末期内径(LVESd)、左室心肌质量(LVM)、左室心肌质量指数(LVMl)和E/A等超声指标,并检测体重指数(BMI)、血脂和空腹血糖。结果:不论NT组还是EH组,高脂血症组和非高脂血症组间的LVEDd、LVESd、LVM、LVMI均无统计学差异,高脂血症组的E/A低于非高脂血症组;Mantel-Haenszel检验显示两组间左室重构的检出率无统计学意义。结论:高脂血症在新疆哈萨克族正常血压组和高血压组左室重构中可能不起作用,但可引起左室舒张功能障碍。
Objective: To investigate the effect of hyperlipidemia on left ventricular remodeling and left ventricular function in Kazak normotensive and hypertensive rats in Xinjiang Uygur Autonomous Region. Methods: A total of 352 Kazaks in Changji, Xinjiang were selected as the study subjects. Among them, 213 were in the normal group (NT) and 139 in the hypertensive group (EH). The left ventricular diastolic diameter (LVEDd), left ventricular end-systolic (LVESd), left ventricular mass (LVM), left ventricular mass index (LVMl) and E / A were measured. Body mass index (BMI), serum lipids and fasting blood glucose were measured. Results: There was no significant difference in LVEDd, LVESd, LVM and LVMI between the hyperlipidemia group and the non-hyperlipidemia group, both in NT group and EH group. The E / A in hyperlipemia group was lower than that in non-hyperlipidemia group Serum group; Mantel-Haenszel test showed that the detection rate of left ventricular remodeling between the two groups was not statistically significant. Conclusion: Hyperlipemia may not play a role in left ventricular remodeling in Kazak normotensive and hypertensive groups in Xinjiang, but it may cause diastolic dysfunction in left ventricle.