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目的分析肝硬化并发糖尿病患者的临床特征,探讨肝源性糖尿病的发病机制及治疗方法。方法对62例肝硬化并发糖尿病患者与同期住院56例肝硬化无糖尿病患者从临床及实验室表现、治疗效果进行对照研究。结果肝硬化并发糖尿病者临床表现以消化道症状为主,糖尿病症状不典型。肝功能越差,糖尿病发生率越高,并发症越多,病死率高。结论肝硬化并发糖尿病时糖尿病临床表现不明显,应常规检查尿糖和血糖,及时诊断和控制糖代谢异常,可以有效地改善肝硬化患者的预后。
Objective To analyze the clinical features of patients with cirrhosis complicated with diabetes mellitus and to explore the pathogenesis and treatment of liver-derived diabetes mellitus. Methods Sixty-two patients with cirrhosis and diabetes mellitus and 56 patients with non-diabetic liver cirrhosis from the clinical and laboratory performance and control were studied. Results The clinical manifestations of liver cirrhosis and diabetes were mainly gastrointestinal symptoms and the symptoms of diabetes were not typical. The worse the liver function, the higher the incidence of diabetes, the more complications, high mortality. Conclusions The clinical manifestations of diabetes mellitus are not obvious when patients with cirrhosis and diabetes mellitus. Urine and blood glucose should be routinely examined, and timely diagnosis and control of abnormal glucose metabolism can effectively improve the prognosis of patients with cirrhosis.