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观察腹腔感染患者及动物模型的血IL—8变化，结果显示，感染动物组术后3h开始IL—8明显升高，于24h达高峰，同时体温升高，白细胞数及中性粒细胞比例明显上升，感染患者组术前及术后1天IL—8含量增高，术后5天下降，但都明显高于对照组。严重感染时IL—8升高在中性粒细胞的粘附、渗出及游走中起重要作用，对腹腔感染的预后有着一定的意义。
The changes of blood IL-8 levels in patients with abdominal infection and in animal models were observed. The results showed that the IL-8 levels of infected animals increased significantly at 3h after operation and peaked at 24h, meanwhile the body temperature increased, the number of white blood cells and neutrophils increased significantly The levels of IL-8 in patients with infection and infection were increased at 1 day and 5 days after operation, but both were significantly higher than those in control group. Serious infection of IL-8 increased neutrophil adhesion, exudation and migration play an important role in the prognosis of abdominal infection has a certain significance.