论文部分内容阅读
目的探讨同型半胱氨酸和纤维蛋白原在诊断急性脑梗死中的价值。方法将我院自2013年1月至2014年12月间收治的50例急性脑梗死患者作为研究组,随机选择同期入院接受体检的健康者50例为对照组,分别检测两组对象体内同型半胱氨酸和纤维蛋白原的水平,比较组间差异。结果研究组患者HCY、MPV、CRP和FIB等各项指标均高于对照组健康对象(P<0.01),HCY+FIB的敏感度、特异性、阳性预测值和阳性似然比均显著高于四项指标单项测定值(P<0.01)。结论在脑梗死患者的早期诊断、预防和治疗中HCY和FIB的联合检测具有积极的指导意义与临床价值,应进行进一步的深入研究。
Objective To investigate the value of homocysteine and fibrinogen in the diagnosis of acute cerebral infarction. Methods Fifty patients with acute cerebral infarction who were admitted to our hospital from January 2013 to December 2014 were selected as the research group and randomly selected 50 healthy subjects who were admitted to the hospital during the same period as the control group. Cystine and fibrinogen levels were compared between groups. Results The HCY, MPV, CRP and FIB in study group were higher than those in control group (P <0.01). The sensitivity, specificity, positive predictive value and positive likelihood ratio of HCY + FIB in HCY + FIB group were significantly higher than those in control group Four indicators of a single measured value (P <0.01). Conclusion The combined detection of HCY and FIB in the early diagnosis, prevention and treatment of patients with cerebral infarction has a positive guiding significance and clinical value, further research should be carried out.