方法 66例研究对象的年龄为9天至24岁(平均8.6岁),其中14例年龄<3个月。38例心脏结构正常。28例为先心病患者,其中14例为心脏手术后。在应用索他洛尔前,55例(83％)对1种以上的抗心律失常药无效。46例单用索他洛尔,20例并用地高辛。索他洛尔的平均剂量为135mg/m~2/d(4.3mg/kg),分2次口服,治疗时间平均为13.3个月。结果索他洛尔的总有效率为79％,而年龄<3个月的完全有效率为86％。折返性室上速的有效率为89％;房性心动过速为 Methods Sixty-six subjects were aged 9 days to 24 years (mean 8.6 years), 14 of whom were <3 months old. 38 cases of normal heart structure. 28 patients with congenital heart disease, of which 14 patients after cardiac surgery. Before the use of sotalol, 55 (83%) had no effect on more than one antiarrhythmic agent. Forty-six patients received sotalol alone and 20 patients received digoxin. The average dose of sotalol 135mg / m ~ 2 / d (4.3mg / kg), 2 times orally, the average treatment time was 13.3 months. Results The total effective rate of sotalol was 79%, while the full effective rate of <3 months was 86%. The reentry ventricular tachycardia efficiency was 89%; atrial tachycardia was