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β_2球蛋白(β_2 microglobulin,β_2m)是一种相对分子量低的蛋白质。与免疫球蛋白在分子结构上具有同源性。在血清、尿液、唾液及关节腔液中都能检出低浓度的β_2m。笔者以前的研究表明,唾液β_2m浓度检测对于诊断Sjogren综合征具有显著的临床意义。与其他诊断方法比较,此种方法具有较高的敏感性和较强的疾病特异性。
β_2 globulin (β_2m) is a relatively low molecular weight protein. And immunoglobulins in the molecular structure of homology. Low concentrations of β_2m can be detected in serum, urine, saliva and joint fluid. Previous studies by the author indicated that the detection of salivary β_2m concentration has a significant clinical significance for the diagnosis of Sjogren’s syndrome. Compared with other diagnostic methods, this method has high sensitivity and strong disease specificity.