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目的了解宁波市江东区疑似预防接种异常反应(AEFI)分布特征。方法采用描述流行病学方法,对江东区2010-2015年AEFI监测个案数据进行分析。结果全区2010-2015年共报告AEFI个案253例,年均报告发生率为37.11/10万剂。AEFI报告数集中在5-6月份,男女性别比为1∶1.04,发生年龄以0岁组所占比例最高(113例,44.66%)。在所有AEFI中,不良反应占96.84%(245例),包括一般反应213例、异常反应32例。205例(83.67%)不良反应在接种后1d内发生。AEFI报告例数以无细胞百白破联合疫苗最多(47例),报告发生率以麻疹腮腺炎联合减毒活疫苗最高(2 059.93/10万剂)。结论江东区AEFI监测敏感性较高,疫苗接种安全性良好。需进一步加强规范化接种和AEFI监测质量。
Objective To understand the distribution of suspected immunization anaphylaxis (AEFI) in Jiangdong District of Ningbo City. Methods Descriptive epidemiological methods were used to analyze the data of AEFI surveillance cases in Jiangdong District during 2010-2015. Results A total of 253 AEFI cases were reported in the whole district from 2010 to 2015, with an average annual incidence of 37.11 / 10 000 doses. The number of AEFI reports concentrated in May-June, the male-female ratio was 1: 1.04, and the age of onset was the highest among 0-year-olds (113 cases, 44.66%). In all AEFIs, adverse reactions accounted for 96.84% (245 cases), including 213 cases of general reaction and 32 cases of abnormal reaction. 205 (83.67%) adverse reactions occurred within 1 day after inoculation. The number of cases reported by AEFI was the highest (47 cases), and the highest incidence of measles mumps combined with attenuated live vaccine was 2 059.93 / 10 000. Conclusion The sensitivity of AEFI surveillance in Jiangdong District is high and the safety of vaccination is good. Need to further strengthen the standardized vaccination and AEFI monitoring quality.