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目的探讨缺血修饰白蛋白(Ischemia modified albumin,IMA)在心肌缺血早期的诊断价值。方法测定急性冠脉综合征(acute coronary syndrome,ACS)患者在心肌缺血早期的缺血修饰白蛋白水平,并与同期健康对照组比较并分析。结果 ACS组[(85.3±19.7)U/ml]血清IMA水平显著高于健康对照组[(59.3±5.4)U/ml]。结论 IMA是最敏感的ACS早期缺血指标,与传统心肌缺血标志物联合应用能极大减少ACS漏诊率。
Objective To investigate the diagnostic value of Ischemia modified albumin (IMA) in the early stage of myocardial ischemia. Methods The levels of ischemia-modified albumin in patients with acute coronary syndrome (ACS) at the early stage of myocardial ischemia were determined and compared with those of healthy controls at the same period. Results Serum IMA of [(85.3 ± 19.7) U / ml] in ACS group was significantly higher than that in healthy control group [(59.3 ± 5.4) U / ml]. Conclusion IMA is the most sensitive index for early ischemic stroke. Combined with traditional myocardial ischemia markers, IMA can greatly reduce the misdiagnosis rate of ACS.