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采用旋转包衣法研制4.5%敌百虫·毒死蜱颗粒剂,并通过优化组合法对助剂和填料进行试验筛选和优化,确定了最优配方为:敌百虫3%;毒死蜱1.5%;稳定剂环氧氯丙烷2%;黏结剂黄原胶(XG)0.2%;吸附剂白碳黑+轻质碳酸钙6%+1%;着色剂碱性紫0.15%;载体砂补足100%.用该配方配制的样品产品质量稳定合格,流动性好,热贮(54±2℃,14d)分解率敌百虫≤6%,毒死蜱≤5%,脱落率≤3%,各项指标符合颗粒剂的要求.“,”Development of 4.5% trichlorfon and chlorpyrifos granule by rotary coating method,and the additives and fillers test screening and optimization by optimization method,the optimum formula was:trichlorfon3%;chlorpyrifos1.5%;stabilizer epichlorohydrin 2%;adhesive xanthan gum(XG)0.2%;white carbon adsorbent + calcium carbonate 6%+1%;0.15% basic violet colorant carrier is made up of 100% sand. Qualified quality compounded with the formula of sample product stability,good fluidity,heat storage(54±2℃,14d)the decomposition rate of trichlorfon is less than 6%,less than 5% of chlorpyrifos,shedding rate is below 3%,the indicators meet the requirements of granules.