1987年10月,美国北卡罗纳州海滨受鳓一次由短裸藻引起赤潮的影响,造成海水变色、鱼死亡,人吃了受赤潮影响的贝类(牡蛎、蛤)发生神经性贝类中毒(neurotoxic shellfish poisoning NSP)。作者对中毒病人进行了临床和流行病学调查研究。具体方法是,通过与海岸线各国家建立联络中心,及时了解海岸线区域有关的渔业状况,规定凡在10月23日之后吃过贝类而患神经和胃肠道系统疾病的人均列入个案调查对象范围内,同时对赤潮水直接镜检,结果每升中短裸藻含量大于5000,而且吃了受赤潮影响贝类必在24 h内有中毒症状且至少持续1 h的病人作为回顾性分析的对象,贝 In October 1987, the coast of North Carolina in the United States was subjected to a red tide caused by short-eared algae, causing discoloration of the seawater and killing of fish. People eating shellfish (oysters, clams) affected by red tides were found to have neurological shellfish Neurotoxic shellfish poisoning (NSP). The author of the poisoning patients were clinical and epidemiological investigation. The specific method is to keep abreast of the state of fisheries in the coastline areas by establishing contact centers with the countries in the coastline and stipulate that all those suffering from neurological and gastrointestinal diseases who have eaten shellfish after October 23 should be included in the case investigation , And at the same time, the microscopic examination of red tide water was carried out directly. As a result, the content of small and medium euglena per liter was more than 5000, and the patients infected with red tide affected shellfish would have poisoning symptoms for at least 1 h within 24 h as a retrospective analysis Objects, shellfish