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研究了发酵灵芝粉中肽类化合物的分离及其生物活性。将发酵灵芝粉的水和醇提取物上离子交换树脂柱，依次用酸性、中性、碱性淋洗液洗脱分组，发现中性洗脱部分对羟基自由基抑制作用最强，抑制率最高可达８１％；碱性洗脱部分亦具有抑制羟基自由基的效果；酸性洗脱部分抑制羟基自由基的作用不强，且占很少比例。经体外抗肿瘤试验，初步确定超滤膜过滤物具有较好地抑制肿瘤效果。
The separation of peptide compounds in the fermentation of Ganoderma lucidum powder and its biological activity were studied. The water and alcohol extract of the fermented Ganoderma lucidum powder was ion-exchange resin column, followed by acidic, neutral, alkaline eluent elution grouping and found that the neutral elution part of the strongest inhibition of hydroxyl radicals, the highest inhibition rate Up to 81%; alkaline elution part also has the effect of inhibiting hydroxyl radicals; acid elution part of the inhibition of hydroxyl radicals is not strong, and accounted for a small proportion. The antitumor test in vitro, initially identified ultrafiltration membrane filter has better inhibition of tumor effect.