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目的:分析影响急性冠脉综合征高龄患者PCI术后预后的危险因素。方法:选取3年来我科住院72例接受PCI术的急性冠脉综合征患者,按年龄分为:高龄组,年龄≥75岁,共36例;低龄组,年龄<75岁,共36例。分析高龄患者PCI术后的HbA1c、NT-proBNP、血小板聚集率(PAGR)与随访1年后LVEF、LVEDd值的相关性。比较两组的主要不良心脏事件(MACE),即再梗塞率及死亡率之间的差异。结果:高龄患者的NT-proBNP、PAGR与LVEF值呈负相关关系,相关系数为-0.891和-0.901,与LVEDd值呈正相关关系,相关系数为0.857和0.924。而HbAlc与LVEF、L-VEDd值无明显相关性。两组的MACE(再梗塞率及死亡率)部存在差异性,P值分别为0.0148与0.0254。结论:急性冠脉综合征高龄患者PCI术后MACE较低龄患者发生率高,且心脏功能与NT-proBNP及PAGR有相关性。
Objective: To analyze the risk factors affecting the prognosis of elderly patients with acute coronary syndrome after PCI. Methods: A total of 72 hospitalized patients with acute coronary syndrome who underwent PCI during the past three years were enrolled in this study. They were divided into three groups according to their ages: age group> 75 years old, 36 cases in total. The correlation between HbA1c, NT-proBNP, platelet aggregation rate (PAGR) and LVEF and LVEDd after one year follow-up in elderly patients was analyzed. The major adverse cardiac event (MACE) was compared between the two groups, the difference between the rates of reinfarction and mortality. Results: There was a negative correlation between NT-proBNP, PAGR and LVEF in elderly patients, the correlation coefficient was -0.891 and -0.901, and there was a positive correlation with LVEDd, the correlation coefficient was 0.857 and 0.924. There was no significant correlation between HbAlc and LVEF and L-VEDd. There was a difference in MACE between the two groups (P = 0.0148 and 0.0254, respectively). Conclusion: The incidence of MACE in elderly patients with acute coronary syndrome after PCI is relatively high, and the correlation between cardiac function and NT-proBNP and PAGR is significant.