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目的探讨2型糖尿病(T2DM)患者颈动脉和下肢动脉粥样硬化(AS)的相关性。方法对221例T2DM患者行双侧颈动脉及下肢动脉彩超检查,根据彩超结果将颈动脉和下肢动脉粥样硬化分为0~4级,同时检测空腹血糖(FPG)、空腹胰岛素(FINS)、糖化血红蛋白(HbA1C)、血脂、血压。结果年龄、FINS、lnHOMA-IR为颈动脉和下肢动脉病变共同的危险因素。HbA1C为下肢动脉病变的危险因素。结论颈动脉与下肢动脉粥样硬化程度呈等级正相关,但二者粥样硬化的危险因素不尽相同。
Objective To investigate the association between carotid and lower extremity atherosclerosis (AS) in type 2 diabetes mellitus (T2DM). Methods A total of 221 T2DM patients underwent color Doppler ultrasound examination of bilateral carotid and lower extremity arteries. The atherosclerosis of the carotid and lower extremities was divided into four grades according to the results of color Doppler ultrasound. Fasting plasma glucose (FPG), fasting insulin (FINS) Glycosylated hemoglobin (HbA1C), lipids, blood pressure. Results Age, FINS and lnHOMA-IR were common risk factors of carotid artery and lower extremity arterial disease. HbA1C is a risk factor for lower extremity arterial disease. Conclusions There is a positive correlation between the carotid artery and the degree of atherosclerosis in the lower extremities. However, the risk factors for atherosclerosis are not the same.