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目的就缩宫素配伍地塞米松预防产后出血的临床应用进行探讨。方法选择2010年1月~2013年1月间我院收治的剖宫产产妇300例,按照分娩个数的奇、偶数分为两组,分别为对照组(缩宫素组)和观察组(缩宫素配伍地塞米松组),比较两组疗效。结果观察组150例患者30分钟出血量为(130.0±20.7)ml,2小时累计出血量为(179±64)ml;对照组150例患者30分钟出血量为(180.0±36.1)ml,2小时累计出血量为(237±80)ml。两组具有较为明显的统计学差异,具有统计学意义(P<0.05)。观察组150例患者第三产程时间为(8.7±3.2)钟,出血500~100ml的有9例,出血>1000ml的有4例。两组具有较为明显的统计学差异,具有统计学意义(P<0.05)。两组患者均未出现药物毒副反应。结论缩宫素配伍地塞米松预防产后出血的临床效果较好,能够有效地降低产后出血的发生率,明显缩短第三产程,且无不良反应和并发症,值得在临床上大量应用。
Objective To explore the clinical application of oxytocin and dexamethasone in preventing postpartum hemorrhage. Methods 300 cases of cesarean section in our hospital from January 2010 to January 2013 were divided into two groups according to odd and even number of delivery, which were control group (oxytocin group) and observation group ( Oxytocin and dexamethasone group), the two groups were compared. Results The blood loss of 150 patients in observation group was (130.0 ± 20.7) ml for 30 minutes, and (179 ± 64) ml for 2 hours. The control group had a blood loss of (30.0 ± 36.1) ml in 150 patients for 2 hours The cumulative amount of bleeding was (237 ± 80) ml. The two groups have more obvious statistical differences, with statistical significance (P <0.05). In the observation group, the duration of the third stage of labor was (8.7 ± 3.2) minutes in 150 patients, 9 in 500 to 100 mL of hemorrhage, and 4 in> 1000 mL of hemorrhage. The two groups have more obvious statistical differences, with statistical significance (P <0.05). Two groups of patients did not appear drug side effects. Conclusion Oxytocin and dexamethasone combined with dexamethasone in the prevention of postpartum hemorrhage have a good clinical effect, which can effectively reduce the incidence of postpartum hemorrhage, shorten the third stage of labor, and have no adverse reactions and complications. It is worth widely used in clinical practice.