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目的 比较自体角膜缘与自体球结膜移植治疗翼状胬肉的疗效。方法 翼状胬肉病人 88例 (96眼 ) ,随机分为A组41例 (4 2眼 ) ,B组 47例 (5 4眼 )。手术显微镜下切除胬肉后A组行自体角膜缘上皮移植术 ,B组行自体球结膜移植术。观察术后角膜创面修复情况 ,翼状胬肉复发率。结果 术后角膜创面修复时间A组较B组快 (P <0 0 1) ,术后 12个月胬肉复发率A组(11 9% )明显低于B组 (2 2 2 2 % ,P <0 0 1)。结论 自体角膜缘上皮移植可为病变区角膜提供新的干细胞来源 ,是治疗翼状胬肉的理想方法。
Objective To compare the efficacy of self-corneal limbal conjunctiva transplantation for the treatment of pterygium. Methods Totally 88 patients (96 eyes) with pterygium were randomly divided into group A (n = 41) and group B (n = 47) (n = 44). A group underwent autograft corneal limbal epithelial transplantation after surgical excision of pterygium underwent surgical operation. Group B received autonomic conjunctival transplantation. Corneal wound healing was observed, the recurrence rate of pterygium. Results The corneal wound repair time was faster in group A than in group B (P <0.01). The recurrence rate of corneal wounds in group A at 12 months after operation was significantly lower than that in group B (122%, P <0 0 1). Conclusion Autologous limbal epithelial transplantation can provide a new source of stem cells for the cornea of the diseased area. It is an ideal method for the treatment of pterygium.