论文部分内容阅读
目的对周围神经病的患者进行皮肤神经活检、临床特点、神经电生理和腓肠神经活检的对比观察。方法观察7例周围神经病患者,进行皮肤神经活检、腓肠神经活检、神经电生理检查,并对这些检查的一致性进行比较。结果7例患者的神经电生理检查均提示有周围神经损害,腓肠神经活检也有不同程度的神经病变。6例皮肤神经活检同时有远近端皮肤神经的异常,且与腓肠神经活检所见病变的严重程度相一致。此6例患者的皮肤神经异常远端重于近端,符合长度依赖性周围神经病变。结论皮肤神经活检与临床特点、神经电生理以及腓肠神经活检的结果有高度一致性;皮肤神经活检可以反映长度依赖性周围神经病变。
Objective To compare the clinical features, nerve electrophysiology and sural nerve biopsy in patients with peripheral neuropathy. Methods Seven patients with peripheral neuropathy were examined for skin nerve biopsy, sural nerve biopsy and electrophysiological examination, and the consistency of these tests was compared. Results 7 cases of neurophysiological examination showed peripheral nerve damage, sural nerve biopsy has varying degrees of neuropathy. Six cases of skin nerve biopsy with near and far side of the skin nerve abnormalities, and with the severity of the lesions seen by sural nerve biopsy. The 6 cases of skin and nerve abnormalities were more distal to the proximal end, consistent with length-dependent peripheral neuropathy. Conclusion Skin nerve biopsy is highly consistent with clinical features, neuroelectrophysiology and sural nerve biopsy results; skin biopsy can reflect length-dependent peripheral neuropathy.