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目的提高对朗格汉斯细胞组织细胞增生症(LCH)的认识。方法回顾分析新疆维吾尔自治区人民医院近5年来诊断的6例成年 LCH 患者的临床、影像资料特点。结果 LCH 肺部病变的放射影像学表现为双肺弥漫结节影,间质纤维化伴多发囊泡形成。1例患者的淋巴结活检标本可见异常的朗格汉斯细胞漫润。结论对肺弥漫性病变的患者应警惕此 LCH 病,并及时行病理学检查,确诊后予放疗、全身化疗治疗。
Objective To improve the understanding of Langerhans cell histiocytosis (LCH). Methods The clinical and imaging features of 6 adult LCH patients diagnosed in the People’s Hospital of Xinjiang Uygur Autonomous Region in recent 5 years were retrospectively analyzed. Results The radiological manifestations of pulmonary lesions in LCH were diffuse nodules in both lungs and interstitial fibrosis with multiple vesicles. Lymph node biopsy specimens of 1 patient showed abnormal Langerhans cell infiltration. Conclusion Patients with diffuse pulmonary lesions should be alert to this LCH disease and timely pathological examination, radiotherapy and systemic chemotherapy after diagnosis.