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目的:对奥曲肽用于治疗急性非门脉高压性上消化道大出血的临床疗效进行分析。方法:选择2012年10月-2014年8月本院收治的急性非门脉高压性上消化道出血的患者70例,随机分为对照组、观察组,对照组患者采用常规止血方法进行治疗;观察组患者在相同的常规止血治疗的基础上配合使用奥曲肽治疗,观察记录患者呕血、便血情况、监测患者生命体征变化情况及药物不良反应等情况。结果:观察组治疗总有效率高达94.3%,对照组治疗总有效率达71.4%,组间比较,差异具有统计学意义(P<0.05)。结论:临床治疗急性非门脉高压性上消化道出血采用常规止血措施配合奥曲肽进行止血治疗,疗效更佳,起效迅速、且没有明显的不良反应。
Objective: To analyze the clinical efficacy of octreotide in the treatment of acute non-portal hypertensive upper gastrointestinal hemorrhage. Methods: Seventy patients with acute non-portal hypertensive upper gastrointestinal bleeding admitted to our hospital from October 2012 to August 2014 were randomly divided into control group, observation group and control group. The patients in the observation group and control group were treated by conventional hemostasis. Patients in the observation group were treated with octreotide on the basis of the same conventional hemostatic treatment. The vomit blood and blood in the stool were observed and recorded. The changes of vital signs and adverse drug reactions were observed. Results: The total effective rate was 94.3% in the observation group and 71.4% in the control group. The differences between the two groups were statistically significant (P <0.05). Conclusion: The clinical treatment of acute non-portal hypertensive upper gastrointestinal bleeding with conventional hemostatic measures in conjunction with octreotide hemostasis, better efficacy, rapid onset, and no significant adverse reactions.