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目的观察不同急诊溶栓药物治疗急性心肌梗死的临床效果。方法选取医院收治的急性心肌梗死患者120例为研究对象,随机分为A、B、C 3组,每组40例。A组为对照组采用硝酸甘油和低分子肝素治疗,B组采用尿激酶治疗,C组采用链激酶治疗,观察3组患者心电图ST段变化,测定血小板计数(PLT)、活化部分凝血酶时间(APTT)、部分凝血酶原时间(PT),并根据测定结果进行对比分析。结果 B组、C组总有效率分别为95.0%、92.5%,均高于A组的82.5%(P<0.05);治疗后,3组心电图ST段下降、PLT、APTT、PT均有一定改善,且B组、C组均优于A组(P<0.05)。结论应用溶栓治疗方案对急性心肌梗死患者效果显著,尿激酶的治疗效果略好于链激酶,值得临床推广应用。
Objective To observe the clinical effects of different emergency thrombolytic drugs in the treatment of acute myocardial infarction. Methods A total of 120 acute myocardial infarction patients admitted to hospital were selected as study objects and randomly divided into A, B and C groups, 40 cases in each group. Group A was treated with nitroglycerin and low molecular weight heparin; Group B was treated with urokinase; Group C was treated with streptokinase; ST segment electrocardiographic changes were observed in three groups; platelet count (PLT) and partial thromboplastin time APTT), partial prothrombin time (PT), and based on the results of the comparative analysis. Results The total effective rates of group B and group C were 95.0% and 92.5%, respectively, which were higher than those of group A (82.5%, P <0.05). After treatment, ST segment of electrocardiogram decreased and PLT, APTT and PT were improved , And group B and group C were better than group A (P <0.05). Conclusion The application of thrombolytic therapy in patients with acute myocardial infarction significant effect, the treatment of urokinase slightly better than streptokinase, worthy of clinical application.