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探讨首发重症抑郁障碍患者应激生活事件(SLE)暴露的特征,对2009年~2013年261例首发抑郁障碍患者(15岁~79岁)进行访谈调查。结果显示,全部261例患者过去12个月内SLE的发生率为71.6%;首发抑郁障碍患者最常见的5类生活事件分别为:躯体疾病(19.8%)、社交/人际冲突(18.7%)、失业/工作学习(18.7%)、离异/婚恋问题(12.8%)、丧亲(9.6%);女性较男性暴露更多的社交/人际冲突和其他应激事件;不同年龄患者的SLE构成差异有统计学意义(P<0.01),其中躯体疾病、社交/人际冲突事件随着年龄增加显著增多。“,”To explore the characteristics of stressful life events (SLE) preceding the onsets of the first‐episode of major depression disorder (MDD) .261 patients diagnosed with MDD (15 to 79 years old) were interviewed by psychiatrists during 2009 to 2013 .The results showed that the incidence of SLE was 71 .6% in the last 12 months .The most common top five types of SLE were:somatic diseases (19 .8% ) ,social/interpersonal conflict (18 .7% ) ,unemployment/work problem (18 .7% ) ,divorced/marriage problems (12 .8% ) and bereavement (9 .6% ) .Women were more likely than men to be exposed to social/interpersonal conflict and other stress life events .The SLE component were different in different age groups (P<0 .01) ,with disease and social/interpersonal events increasing with age .