论文部分内容阅读
目的探索宫颈锥切术(LEEP术)对宫颈上皮内瘤样病变的诊断和治疗疗效。方法回顾性研究2010年1-12月40例宫颈上皮内瘤样病变(CIN)患者(阴道镜活检初步诊断)在我所行LEEP术的诊断、治疗和预后。结果所有患者接受了宫颈锥切术。在宫颈锥切术和阴道镜活检的病理诊断之间有显著性差异。35例宫颈锥切术和阴道镜活检诊断结果一致(87.5%)。3例病理结果程度加重,其中1例病理结果为鳞状上皮细胞癌已住院治疗。2例病理结果程度减轻。有1例术后病理为CINⅢ级的患者,切缘见残余病灶,术后随访2年未见异常细胞。其他病患,包括行子宫切除术者,至今未见复发。结论 LEEP术可作为CIN的治疗与术后组织切缘病理阴性的首要选择,但患者手术应后随访密切。
Objective To explore the diagnostic and therapeutic effect of cervical conization (LEEP) on cervical intraepithelial neoplasia. Methods The clinical data of 40 patients with cervical intraepithelial neoplasia (CIN) from January 2010 to December 2010 were analyzed retrospectively. The diagnosis, treatment and prognosis of LEEP were performed in our department. Results All patients underwent cervical conization. There was a significant difference between the pathological diagnosis of cervical conization and colposcopy biopsy. 35 cases of cervical conization and colposcopy biopsy diagnosis of the same (87.5%). Three cases of pathological results increased, one case of pathological results squamous cell carcinoma has been hospitalized. 2 cases reduced the degree of pathological results. One case of postoperative pathology CIN Ⅲ grade, cutting edge see residual lesions, no abnormal cells were observed after 2 years of follow-up. Other patients, including those who underwent hysterectomy, have not seen any recurrence so far. Conclusions LEEP can be used as the first choice for the treatment of CIN and negative pathology after operation, but the patients should follow up closely after operation.