目的评估等亮度颜色图像翻转视诱发电位（ＣＰＲＶＥＰ）作为一种客观色觉检查在原发性开角型青光眼（ＰＯＡＧ）所致的后天性色觉障碍的临床意义。方法对３１眼原发性开角型青光眼和３３眼正常对照测定ＣＰＲＶＥＰ，包括白／黑、红／黑、绿／黑、蓝／黑、红／绿和蓝／黄７种颜色棋盘格。所有被检查者同时作ＦＭ１００ｈｕｅ试验。结果ＰＯＡＧ患者的所有颜色ＣＰＲＶＥＰＰ１潜时均明显延长，而Ｐ１波幅除蓝／黑外无明显变化。结论ＰＯＡＧ所有颜色通道均受损，尤其是蓝／黑通道受损最严重，ＣＰＲＶＥＰ的Ｐ１潜时和蓝／黑Ｐ１波幅是判断ＰＯＡＧ所致的后天性色觉障碍的敏感指标 Objective To evaluate the clinical significance of inverted light-induced evoked potentials (CPR-VEP) as an objective colorimetric method for the detection of acquired photodamage caused by primary open-angle glaucoma (POAG). Methods CPRVEP was measured in 31 eyes with primary open-angle glaucoma and 33 eyes with seven color chessboard including white / black, red / black, green / black, blue / black, red / green and blue / yellow . All subjects were tested for FM100 hue at the same time. Results All patients with POAG color CPR  VEPP1 latency were significantly prolonged, and P1 amplitude except blue / black no significant change. Conclusions All channels of POAG are impaired, especially blue / black channel. The P1 latency and blue / black P1 amplitude of CPR-VEP are the sensitive indexes for judging the color vision disorder caused by POAG