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亚硒酸钠(Na_2SeO_3)是预防克山病的有效药物,本室曾报道它的心血管药理作用和对心脏肌力效应的影响。为深入探讨Na_2SeO_3对完整动物心脏功能的影响,本实验采用改进的非损伤性心功能监测方法观察了Na_2SeO_3对30只麻醉犬心缩间期(STI)的影响,根据STI变化来评价心脏功能。
Sodium selenite (Na_2SeO_3) is an effective drug to prevent Keshan disease, this room has been reported on its cardiovascular pharmacological effects and effects on cardiac muscle strength. In order to further investigate the effect of Na_2SeO_3 on cardiac function in intact animals, the effect of Na_2SeO_3 on cardiac systolic period (STI) in 30 anesthetized dogs was observed by using improved noninvasive cardiac function monitoring method. Cardiac function was evaluated according to STI changes.