宜昌地区HPV分型调查

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目的:调查2011-01-01-2013-01-24三峡大学人民医院人乳头状瘤病毒(HPV)分型感染状况,分析HPV分型与诊断、年龄分布、单一与多重感染、患者孕产流及外伤等状况。方法:以我院LIS系统和病案室为资料来源,收集患者HPV分型感染、年龄分布、单一与多重感染、患者孕产流及外伤等资料。应用SPSS19.0分析不同年龄组、宫颈病变组间的分布差异。结果:宜昌地区妇女感染以HPV16为主(52.22%)。其次为HPV18、HPV52等;HPV感染总数在CINⅠ、CINⅡ、CINⅢ,宫颈癌Ⅰ、Ⅱ、Ⅲ期中差异有统计学意义(P<0.01);40~49岁感染人数最多,为43例(47.78%);HPV感染阳性率在各年龄组间差异有统计学意义(P<0.05);单一感染占77.78%,双重感染占18.89%,三重感染占3.33%;感染者中有3次孕史和1次生产史的最常见;43.9%的患者有外伤史,其中以结扎手术为主。结论:宜昌地区妇女HPV感染亚型以HPV16为主;HPV感染在病理程度、年龄中差异有统计学意义;感染者大多有多孕、多产和流产、外伤史。 Objective: To investigate the typing status of human papillomavirus (HPV) in People’s Hospital of the Three Gorges University from January 2011 to January 2013 and analyze the classification and diagnosis of HPV, age distribution, single and multiple infection, And trauma and other conditions. Methods: The data of LIS system and medical records in our hospital were collected. The patients were divided into genotypes of HPV infection, age distribution, single and multiple infection, maternal pregnancy and trauma. Using SPSS19.0 analysis of different age groups, cervical lesions between the distribution differences. Results: HPV16 was the most common infection in women in Yichang (52.22%). Followed by HPV18, HPV52, etc. The total number of HPV infection was statistically significant (P <0.01) in CINⅠ, CINⅡ, CINⅢ, cervical cancer Ⅰ, Ⅱ, ). The positive rate of HPV infection was significantly different among all age groups (P <0.05). Single infection accounted for 77.78%, double infection accounted for 18.89% and triple infection accounted for 3.33%. There were 3 pregnant and 1 The most common history of birth; 43.9% of patients had a history of trauma, of which the main ligation. Conclusion: HPV16 subtype is predominant in women in Yichang area. HPV infection has statistical significance in pathology and age. Most of the infected patients have multiple pregnancies, multiple births and abortions, and history of trauma.
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