论文部分内容阅读
目的:观察地诺前列酮栓用于可疑羊水过少足月妊娠者促宫颈成熟及引产的有效性和安全性。方法:180例妊娠足月可疑羊水过少初产妇随机分为地诺前列酮组和催产素组,每组90例。催产素组常规静脉滴注催产素。地诺前列酮组于阴道后穹隆放置地诺前列酮栓24h后取出,出现临产、强直性宫缩、胎儿窘迫及恶心、呕吐、低血压、心动过速等不良反应时及时取出栓剂,并静脉滴注催产素,催产素用法、用量同催产素组。比较2组用药12h后宫颈Bishop评分和分娩结局。结果:地诺前列酮组用药后12h宫颈Bishop评分(8.03±1.12)分,引产成功率96.67%,剖宫产率27.78%;催产素组用药后12h宫颈Bishop评分(5.15±1.05)分,引产成功率43.33%,剖宫产率64.44%,2组比较差异均有统计学意义(P<0.01)。2组胎儿窘迫、羊水污染及新生儿窒息发生率比较差异均无统计学意义(P>0.05)。结论:地诺前列酮栓用于可疑羊水过少足月妊娠引产安全、有效,并可降低剖宫产率。
Objective: To observe the efficacy and safety of dinoprostone suppository in promoting cervical ripening and induction of labor with suspect oligohydramnios. Methods: 180 cases of pregnancy-term suspected oligohydramnios primipara were randomly divided into dinoprostone group and oxytocin group, 90 cases in each group. Oxytocin group conventional intravenous oxytocin. In the dinoprostone group, droperidol suppository was placed in the vaginal posterior fornix for 24h, and then it was taken out for 24 hours. During labor, tonic contractions, fetal distress, nausea, vomiting, hypotension, tachycardia and other adverse reactions, Oxytocin infusion, oxytocin usage, the same amount of oxytocin group. Cervical Bishop score and delivery outcome were compared between the two groups after 12 hours. Results: The cervical Bishop score (8.03 ± 1.12), the induction rate of induction of labor (96.67%) and the rate of cesarean section (12.78%) in the dinoprostone group at 12 hours after treatment were significantly higher The success rate was 43.33% and the rate of cesarean section was 64.44%. There was significant difference between the two groups (P <0.01). There was no significant difference in the incidence of fetal distress, amniotic fluid contamination and neonatal asphyxia between the two groups (P> 0.05). CONCLUSION: The use of dinoprost suppository is safe and effective in inducing abortion in children with suspected oligohydramnios, and can reduce the rate of cesarean section.