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采集114例心肌炎病人和40例对照组 (非心肌炎健康人)咽拭子和血清标本,进行病毒分离和病毒中抗体测定。结果、心肌炎组分离出柯萨奇B组病毒、流感病毒、腺病毒等32株。对照组均未分离出病毒。从病毒分离阳性的18例双份血清中、其中和抗体≥4倍升高者15例,阳性占83.3％。 心肌炎组的59例R份血清中,其抗体≥4倍升高 39例(COXB病毒抗体占30例)阳性为 66.1％、55例单份血?其 COXB抗体≥1:320者 21例,阳性为 38.1％。对照组其抗体≥4倍长高者7例,二组 P<0.01。病毒分离和血清学阳性共 76例(COXB占29例)二者有病原学价值占66.3％。
Throat swabs and serum samples from 114 myocarditis patients and 40 control subjects (healthy non-myocarditis) were collected for virus isolation and antibody detection in the virus. Results, myocarditis component isolated Coxsackie B virus, influenza virus, adenovirus and other 32 strains. The control group did not isolate the virus. Among the 18 cases of double sera that were positive for virus isolation, 15 cases were neutralized with a ≥ 4-fold increase of antibodies, and 83.3% of them were positive. Myocarditis group of 59 cases of R serum, the antibody ≥ 4-fold increase in 39 cases (COXB virus antibody accounted for 30 cases) was 66.1%, 55 cases of single blood? The COXB antibody 1: 320 in 21 cases, positive 38.1%. In the control group, the antibody was ≥4 times longer in 7 cases, P <0.01 in the second group. A total of 76 cases of virus isolation and serological positive (29 cases of COXB) have etiological value of 66.3%.