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目的探讨先天性脊柱裂临床特点,寻找病因,提高优生优育率。方法对我院2003年10月以来尸解检出的18例先天性脊柱裂患儿的临床及病理资料进行回顾性总结,分析各类明确或潜在的致畸因素,讨论应对措施。结果 18例孕妇年龄跨度较大,多为外省或本地农村户籍,多人产检不正常,多人有孕初感冒服药史或烟酒嗜好,患儿多合并其它脏器畸形。结论脊柱裂是较常见的先天性神经管畸形,其发病受各类理化因素影响,应进一步加强医疗单位的诊疗技术及科普宣教工作。
Objective To investigate the clinical features of congenital spina bifida, look for the cause and improve the rate of prenatal and postnatal fertility. Methods The clinical and pathological data of 18 cases of congenital spina bifida in our hospital from October 2003 were retrospectively reviewed. All kinds of definite or potential teratogenic factors were analyzed retrospectively, and the corresponding measures were discussed. Results 18 pregnant women had a large age span. Most of them were from other provinces or local rural domicile. Many people did not get normal birth control. Many people had the flu history of taking medicine during the first trimester or the habit of smoking and drinking. The children combined with other organ malformations. Conclusions Spina bifida is a common congenital neural tube deformity. The incidence of spina bifida is affected by various physical and chemical factors. The diagnosis and treatment of medical units and the science popularization and education should be further strengthened.