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目的讨论与分析药物性肝炎应用还原型谷胱甘肽与门冬氨酸钾镁医疗的临床效果。方法本组研究对象来源于我院收治的68例药物性肝炎患者,依据数字表法随机分为试验组和对照组,各组34例。试验组患者应用还原型谷胱甘肽和门冬氨酸钾镁治疗,对照组应用甘草酸二铵注射液治疗。对比两组患者治疗总有效率,治疗前后体内谷丙转氨酶(ALT)、谷草转氨酶(AST)及总胆红素(TB)变化情况,用药后不良反应情况。结果试验组经治疗后治疗总有效率(97.05%)(P<0.05)。结论应用还原型谷胱甘肽协同门冬氨酸钾镁对药物性肝炎治疗,效果明显优于应用甘草酸二铵。
Objective To discuss and analyze the clinical effect of reducing glutathione and potassium and magnesium aspartate in medical hepatitis. Methods The subjects of this study were from 68 patients with drug-induced hepatitis admitted in our hospital. According to the digital meter method, they were randomly divided into experimental group and control group, with 34 cases in each group. Patients in the test group were treated with reduced glutathione and potassium magnesium aspartate, and control group with diammonium glycyrrhizinate injection. The total effective rate, ALT, AST and TB in the two groups were compared before and after treatment. The adverse reactions after treatment were compared. Results The total effective rate of treatment group after treatment was 97.05% (P <0.05). Conclusions The application of reduced glutathione in combination with potassium and magnesium aspartate in the treatment of drug-induced hepatitis, the effect is better than the application of diammonium glycyrrhizinate.