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目的探讨抗震救灾官兵急性高原反应(acute mountain sickness,AMS)发生的敏感超声指标。方法急进高原前后,应用ALOKa公司ProSoundα-10彩色多普勒超声诊断仪对30名健康抗震救灾官兵进行瞬时波强(wave intensity,WI)及相关超声指标的检测,对AMS发生与否进行统计学分析,建立适用于小样本数据的支持向量机(support vecter machine,SVM)模型,采用留一法进行交叉验证,筛选出与AMS发生密切相关的敏感指标组合,应用软件包SPSS 18.0对各指标进行Spearman相关分析。结果①交叉验证筛选出与AMS发生密切相关的敏感指标组合:舒张期心肌速度梯度(MVGD)、室壁中层径向缩短率(mFs)、瞬时加速度波强(W1)、射血时间(1st-2nd)、舒张压(Pmm);②Spearman相关性结果显示:AMS与W1成正相关(P<0.05),与mFs、MVGD、1st-2nd、Pmm无显著线性相关性。结论 mFs、MVGD、1st-2nd、Pmin、W1是AMS发生的敏感指标。
Objective To explore the sensitive ultrasonic indexes of acute mountain sickness (AMS) occurred in officers and soldiers of earthquake relief. Methods Before and after reaching the plateau, we detected the intensity of wave intensity (WI) and related ultrasound indexes of 30 healthy earthquake-stricken officers and soldiers using the ProSoundα-10 color Doppler ultrasonic diagnostic apparatus of ALOKa company to make statistics on whether AMS occurred or not The support vecter machine (SVM) model for small sample data was established. The cross validation method was used to identify the sensitive index combinations closely related to AMS. The software package SPSS 18.0 Spearman correlation analysis. Results ① The cross-validation screened a combination of sensitive indicators closely related to AMS: MVGD, mFs, W1, and 1st- 2nd, Pm). ②Spearman correlation results showed that AMS was positively correlated with W1 (P <0.05), but not significantly correlated with mFs, MVGD, 1st-2nd and Pmm. Conclusion mFs, MVGD, 1st-2nd, Pmin and W1 are sensitive indicators of AMS.