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在10年前,美国神经病学研究院提出:本世纪的最后10年是脑的10年。开始,人们主要视此为促进研究的口号,在脑的10年内真正发生的事情表明,人们获得的认识和取得的迸展远远超出了原来的期望,我们对神经疾病的病理生理和治疗的可能性在认识方面出现了戏剧化的改进。与发生在其他学科的情况一样,这种进步应归功于基础研究向临床的转换。在这些进步中起重要作用的方法学基础为分子生物学和分子基因学以及能反映脑功能活动的成像技术如PET、MRI。下面我们将就分子生物学方面和系统分析方面取得的进展加以介绍。
Ten years ago, the American Academy of Neurology proposed that the last 10 years of this century be the brain for 10 years. Initially, people regarded this as the slogan for promoting research. What actually happened during the first 10 years of the brain shows that people’s awareness and progress have far exceeded their original expectation. Our pathophysiology and treatment of neurological diseases Possibilities A dramatic improvement has been made in understanding. As is the case with other disciplines, this improvement is due to the shift from basic research to clinical practice. The methodological foundations that play an important role in these advances are molecular and molecular genetics and imaging technologies such as PET and MRI that reflect brain function. Below, we will introduce the progress made in molecular biology and systematic analysis.