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目的 探讨肺癌合并肺部感染的临床特点及其影响因素 ,进一步提高肺癌合并肺部感染的识别能力及处理能力 ,改善预后 ,提高生活质量。方法 对我院近十年收治的肺癌合并肺部感染患者 14 95例的临床表现、病理细胞类型、影像学观察、细菌学监测、化放疗及抗菌治疗情况、预后等进行回顾性分析。结果 肺癌合并肺部感染临床上比较常见 ,感染率为 60 8%,临床表现多样性 ,多数病人发生在化放疗后 ,尤其是化放疗期间同时使用皮质激素者。本病预后差。结论 肺癌合并肺部感染临床表现不典型 ,呼吸道症状不明显 ,胸片CT主要表现为阻塞性肺炎和肺不张。病原菌以革兰阴性菌为主。影响因素有 :长期重度吸烟史 ,肺癌本身的慢性消耗 ,瘤体压迫或阻塞支气管致引流不畅 ,化放疗后抵抗力下降以及原有慢性疾病等。文章对肺癌合并肺部感染的治疗进行了初步探讨
Objective To investigate the clinical characteristics of lung cancer complicated with pulmonary infection and its influencing factors to further improve the lung cancer combined with lung infection recognition and handling capacity to improve prognosis and improve quality of life. Methods The clinical manifestations, pathological cell types, imaging observation, bacteriological monitoring, chemoradiotherapy, antibacterial therapy and prognosis of 1495 patients with lung cancer complicated with pulmonary infection admitted to our hospital in recent ten years were analyzed retrospectively. Results Lung cancer complicated with pulmonary infection was more common in clinic. The infection rate was 60.8%. The clinical manifestations were diverse. Most patients had corticosteroids after chemoradiation, especially during chemoradiotherapy. Poor prognosis of the disease. Conclusion The clinical manifestations of lung cancer complicated with pulmonary infection are not typical, the respiratory symptoms are not obvious, and the CT manifestations of chest X-ray are mainly obstructive pneumonitis and atelectasis. Gram-negative bacteria mainly bacteria. Influencing factors are: long-term heavy smoking history, chronic consumption of lung cancer itself, tumor oppression or obstruction caused by bronchial drainage is poor, resistance to chemotherapy after chemotherapy and the original chronic diseases. The article discussed the treatment of lung cancer complicated with lung infection