【摘 要】
：
As a homodimeric glycoprotein, vascular en- dothelial growth factor (VEGF) is a highly specific mitogen of vascular endothelial cells. It can induce proliferati
【机 构】
：
State Key Laboratory of Reproductive Biology
【基金项目】
：
国家重点基础研究发展计划(973计划);中国科学院知识创新工程项目
论文部分内容阅读
As a homodimeric glycoprotein, vascular en- dothelial growth factor (VEGF) is a highly specific mitogen of vascular endothelial cells. It can induce proliferation and migration, and inhibit apoptosis of endothelial cell. VEGF is involved in many processes in the female reproductive system, such as ovulation, periodical changes of endometrium, embryo implantation and development. VEGF plays important roles in some reproductive diseases, including preeclampsia and fetal hypoevolutism in uterus. Based on our studies on angiogenesis and its relevant factors in the female reproductive system these years, the functions of VEGF in female reproductive system are reviewed, and the research prospect and application of VEGF are also discussed.
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