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目的研究系统性红斑狼疮(SLE)患者器官/系统损伤的情况。方法以SLE损伤指数(SDI)评价121例女性和15例男性SLE患者器官/系统的损伤情况。统计学分析采用SPSS软件包。结果SLE患者SDI最小值为0分,最大值9分,平均(1.79±2.22)分。损伤最多的器官是肾脏(39.0%),其次为肌肉骨骼系统(19.9%)和心血管系统(18.4%)。预后和生活环境及病程(10年以下和10年以上)不同,SLE患者SDI值比较差异具有显著性(P<0.05),而不同性别患者SDI值比较差异无显著性(P>0.05)。发病年龄、诊断年龄与SDI值进行相关分析,没有发现其相关性。结论SDI是一有效测定SLE损伤的工具,为更好地判断SLE患者的预后提供了理论依据。
Objective To investigate the organ / systemic injury in patients with systemic lupus erythematosus (SLE). Methods SLE injury index (SDI) was used to evaluate the organ / system injury in 121 women and 15 male SLE patients. Statistical analysis using SPSS software package. Results The minimum SDI of SLE patients was 0, the maximum was 9 and the average was 1.79 ± 2.22. The most damaged organs were the kidneys (39.0%), followed by musculoskeletal system (19.9%) and cardiovascular system (18.4%). The difference of SDI between SLE patients was significant (P <0.05), but there was no significant difference in SDI between different sexes (P> 0.05). Age of onset, age of diagnosis and SDI value were analyzed, no correlation was found. Conclusion SDI is an effective tool for measuring SLE injury and provides a theoretical basis for better judging the prognosis of patients with SLE.