论文部分内容阅读
肿瘤细胞对多种化疗药物产生交叉抗药性是造成肿瘤化疗失败的主要原因 ,随着化疗药物在头颈部肿瘤的广泛应用 ,多药耐药现象在头颈部肿瘤的研究也取得了一定的进展。本文对近年来头颈部肿瘤多药耐药机制及其逆转剂研究进展作一综述。
The cross-resistance of tumor cells to multiple chemotherapeutic drugs is the main cause of tumor chemotherapy failure. With the widespread use of chemotherapeutic drugs in head and neck tumors, the study of multidrug resistance in head and neck tumors has also achieved certain results. progress. This article reviews recent advances in multidrug resistance mechanisms and reversal agents in head and neck cancers.